The Centers for Control and Prevention (CDC), U.S. Food and Drug Administration, state and local health departments, and other clinical and public health partners are investigating a multistate outbreak of severe pulmonary disease associated with e-cigarette product use (devices, liquids, refill pods and cartridges).

As of September 17, 2019, 530 cases have been reported to the CDC, with seven confirmed deaths. All reported cases have a history of using e-cigarette or vaping products. Most patients have reported a history of using e-cigarette products containing THC. Many patients have reported using THC and nicotine. Some have reported the use of e-cigarette products containing only nicotine. The investigation has not identified any specific e-cigarette product or substance that is linked to all cases. No consistent evidence of an infectious cause has been discovered. Therefore, the suspected cause is a chemical exposure.

The CDC has received complete sex and age data on 373 of 530 cases.

• Nearly three fourths (72%) of cases are male
• Two thirds (67%) of cases are 18 to 34 years old
• 16% of cases are under 18 years and 17% are 35 years or older